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The History and Recent Technologies of HIFU (High Intensity Focused Ultrasound)


今回は開催時刻が 14:40-16:10 となります。

会場青葉山キャンパス 医工学研究科 ナノ医工学研究棟 講堂
Prof. Narendra Sanghvi
(CEO, Focus Surgery Inc.;Assoc. Prof., Indiana University School of Medicine)

「The History and Recent Technologies of HIFU (High Intensity Focused Ultrasound)」

High intensity focused ultrasound (HIFU), as a modality to coagulate the tissue to be treated, was started by Professor William Fry’s group in University Illinois in the 1950s. It was first developed as a noninvasive surgical technique that might duplicate some of the results of standard invasive surgery used in psychological and neurological disorders such as Parkinsonism. Their research extended to the development of computer-based, low-intensity ultrasound instrumentation for visualization of the soft tissue, and these works made him the pioneer of medical ultrasound technologies in the United States. After his untimely death in 1968, the group moved to Indiana University, and I joined them in 1973. Meantime, our group demonstrated that HIFU could be used for the destruction of brain tumors, and also studied the use of ultrasound for the detection of breast cancer, but the developed techniques were not widely used. In 1990s, stimulated by suggestions of urlogogists, we developed a transrectal HIFU system with ultrasonic image guidance. Early studies on the use of this system to treat prostate cancer, performed in University of Vienna and Indiana University, showed that the treatment was effective and that the entire gland could be treated without damaging the surrounding tissue. Around 100 HIFU centers around the globe are currently using the updated version of our ultrasonically guided HIFU system. In 2000s, an MRI guided HIFU system was developed by another group, and is currently used to treat uterine fibroids uterine, breast fibroadenomas, and so on. The advantage of MRI over conventional ultrasonic B-mode imaging has been the capability to map tissue temperature. Recently, we have developed a new ultrasound technique to monitor tissue temperature real-time during HIFU treatment. This technique will also be explained in the presentation.
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